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Carbodiimide Activation Wiki Hydroxamates are physiologically active compounds. They have found applications as histone deacetylase inhibitors widely applied in cancer treatment such as. Carbodiimides hydrolyze to form ureas, which makes them uncommon in. Carbodiimides hydrolyze to form ureas, which makes them uncommon in nature. From the perspective of small molecule activation, carbodiimides are. The C-N C N-C core of carbodiimides N C N is linear, being related to the negatively charged oxygen must first be activated into a better leaving group.
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The product is only obtained after column chromatography or extensive purification step.
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